

Pico145
CAS:
Ref. 3D-DQC28716


Product Information
Name:Pico145
Brand:Biosynth
Description:Pico145 is a novel cation channel blocker that inhibits the influx of intracellular calcium ions. It has been shown to inhibit apoptotic cell death in mammalian tissue, as well as cancer cells. Pico145 binds to the hk-2 protein and blocks the opening of non-selective cation channels. This inhibition leads to an increase in cytosolic calcium ion concentration (Ca2+) and a subsequent activation of proapoptotic proteins such as p53, Bax, and Caspase-3.
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Chemical properties
Molecular weight:524.88 g/mol
Formula:C23H20ClF3N4O5
Purity:Min. 95%