Product Information
Name:VIM-15 (β-Lactamase)
Brand:Biosynth
Description:VIM-15 (β-Lactamase) is a metallo-β-lactamase enzyme, which is derived from bacterial sources, particularly Gram-negative bacteria. Its mode of action involves the hydrolysis of β-lactam antibiotics, facilitating bacterial resistance. This enzyme employs zinc ions as cofactors to break the β-lactam ring, rendering these antibiotics ineffective against the bacteria that produce the enzyme. The hydrolysis process disrupts the antibiotic's structural integrity, crucial for its antibacterial activity, thereby nullifying its therapeutic effects.
VIM-15 is primarily studied in the context of research on antibiotic resistance, an escalating problem in clinical settings. Researchers focus on characterizing and understanding the genetic and structural attributes of VIM-15 to develop inhibitors that may potentially restore the efficacy of β-lactam antibiotics against resistant strains. Moreover, it provides insights into the broader category of metallo-β-lactamases, helping to elucidate mechanisms behind microbial resistance, guide the development of novel antimicrobial agents, and refine diagnostic methods for detecting resistance genes in pathogenic bacteria.
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Chemical properties
Technical inquiry about: VIM-15 (β-Lactamase)
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