Caspase substrate
CAS:
Ref. 3D-EC58694
5mg
315.00€
10mg
483.00€
25mg
945.00€
50mg
1,715.00€
100mg
3,074.00€
Product Information
Name:Caspase substrate
Synonyms:
- Z-Ile-Glu-Thr-Asp-AFCZ-IETD-AFC
Brand:Biosynth
Description:Caspase substrates are a class of pharmacological agents that regulate apoptosis. Caspases are proteases that cleave specific proteins in the cell, leading to apoptosis. Pro-apoptotic proteins activate caspases, while anti-apoptotic proteins inhibit them. Caspase substrates can be either pro-caspase or anti-caspase, depending on the desired effect. They may also be used to regulate caspases without affecting their activity. The caspase substrate is cleaved by caspases and releases a polypeptide fragment that triggers apoptosis in some cells, but not others. For example, the Hl-60 cell line is resistant to the pro-apoptotic effects of the substrate because it contains an anti-apoptotic protein called Bcl-2. In contrast, myocardial cells contain pro-apoptotic proteins and are sensitive to the pro-apoptotic effects of the substrate. In
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:821.75 g/mol
Purity:Min. 95%
Technical inquiry about: Caspase substrate
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