4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-glucopyranoside
CAS:
Ref. 3D-EM182013
10mg
321.00€
25mg
579.00€
50mg
989.00€
100mg
1,507.00€
Product Information
Name:4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-glucopyranoside
Synonyms:
- 4-Methylumbelliferyl N-acetyl-a-D-glucosaminide4MU-a-GlcNAc
Brand:Biosynth
Description:4-Methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside is a fluorogenic substrate for alpha-N-acetylglucosaminidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranosideas a substrate for measuring the alpha-N-acetylglucosaminidase activity is used for Sanfilippo syndrome B screening and mucopolysaccharidosis diagnosis.
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Chemical properties
Molecular weight:379.36 g/mol
Formula:C18H21NO8
Purity:Min. 98 Area-%
Color/Form:Powder
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