4-5-(4-Pyridylmethylamino)pyrazolo1,5-apyrimidin-3-ylbenzamide
CAS:
Ref. 3D-EP176312
10mg
140.00€
25mg
223.00€
Product Information
Name:4-5-(4-Pyridylmethylamino)pyrazolo1,5-apyrimidin-3-ylbenzamide
Brand:Biosynth
Description:Selective inhibitor of the mutated RET variant RETV804M, which is the anticipated drug-resistant RET mutant that can occur in tumours treated with kinase inhibitors. The compound has a biochemical IC50 of 0.02 µM and selectivity for purified RETV804M over purified RET and KDR of 3.7 and 110, respectively. The efficacy of the compound was shown also in cell cultures with IC50 of 4.4 µM, and cell assay selectivity for RETV804M over RET and KDR of 0.89 and 2.3, respectively.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:344.37 g/mol
Purity:Min. 98 Area-%
Color/Form:Powder
Technical inquiry about: 4-5-(4-Pyridylmethylamino)pyrazolo1,5-apyrimidin-3-ylbenzamide
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.