![(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4 ,3-α]pyrazin-7(8H)-yl)-4-(2,4,5-t…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FFA10819.webp&w=3840&q=75)
(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4 ,3-α]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate anhydrous
CAS:
Ref. 3D-FA10819
10g
264.00€
25g
428.00€
50g
635.00€
100g
1,001.00€
250g
1,734.00€
Product Information
Name:(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4 ,3-α]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate anhydrous
Synonyms:
- Sitagliptin phosphate anhydrous
Brand:Biosynth
Description:(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4 ,3-α]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate anhydrous (TZP) is a drug candidate for the treatment of diabetes. TZP is a prodrug that is metabolized by the liver and gut to the active compound sitagliptin phosphate (SGP). TZP has been shown to reduce plasma glucose levels in diabetic rats. In vitro experiments have shown that TZP inhibits dipeptidyl peptidase IV (DPP-IV), which is an enzyme that degrades incretins such as glucagon like peptide 1 and glucose dependent insulinotropic polypeptide. These findings suggest that TZ
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Chemical properties
Molecular weight:505.31 g/mol
Formula:C16H15F6N5O•H3O4P
Purity:Min. 98 Area-%
Color/Form:Powder
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