Ac-Asp-Glu-Val-Asp-AMC ammonium salt
CAS:
Ref. 3D-FA110568
2mg
362.00€
5mg
642.00€
10mg
1,056.00€
25mg
1,987.00€
50mg
3,365.00€
Product Information
Name:Ac-Asp-Glu-Val-Asp-AMC ammonium salt
Synonyms:
- Ac-DEVD-AMC ammonium salt
Brand:Biosynth
Description:Ac-Asp-Glu-Val-Asp-AMC ammonium salt is a small molecule that is used as a tool to study apoptosis in vitro. Ac-Asp-Glu-Val-Asp-AMC ammonium salt induces apoptosis by blocking the mitochondrial membrane potential and inducing the release of cytochrome c from mitochondria into the cytoplasm. This drug also induces activation of caspase 3, which initiates the cascade of events leading to cell death. Ac-Asp-Glu-Val-Asp-AMC ammonium salt has been shown to have an antiangiogenic effect on hl60 cells. This effect may be due to its ability to inhibit expression of survivin, a protein that protects cells from apoptosis. The efficacy of this drug in an experimental model has been shown to be dependent on toll like receptor (TLR) signaling pathways and mitochondrial function.br>
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Chemical properties
Molecular weight:692.67 g/mol
Formula:C30H37N5O13•NH3
Purity:Min. 97 Area-%
Color/Form:Powder
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