Z-Asp-Glu-Val-Asp-chloromethylketone
CAS:
Ref. 3D-FA111069
1mg
314.00€
2mg
474.00€
5mg
798.00€
10mg
1,307.00€
25mg
2,769.00€
Product Information
Name:Z-Asp-Glu-Val-Asp-chloromethylketone
Synonyms:
- Z-DEVD-CMK
Brand:Biosynth
Description:Z-Asp-Glu-Val-Asp-chloromethylketone is a reactive compound that inhibits the activity of proteases and induces neuronal death. Z-Asp-Glu-Val-Asp-chloromethylketone has been shown to induce necrotic cell death in malignant brain cells and has neurotrophic properties. It also causes mitochondrial membrane depolarization, which leads to mitochondrial cytochrome c release and subsequent apoptosis. The reaction mechanism is still unclear but it may involve hydrogen bonding between the ketone group and the amide nitrogen atom of the aspartate residue.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:643.04 g/mol
Formula:C27H35ClN4O12
Purity:Min. 95%
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