Anilofos
CAS:
Ref. 3D-FA40977
Product Information
Name:Anilofos
Brand:Biosynth
Description:Anilofos is a genotoxic compound that has been shown to be metabolized by esterases and glucuronidases, with hydrolysis being the major route of elimination. Anilofos binds to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Anilofos also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
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Chemical properties
Purity:Min. 95%