Product Information
Name:5-Bromonicotinoyl chloride
Brand:Biosynth
Description:5-Bromonicotinoyl chloride is a synthetic compound that has been shown to be an inhibitor of some cancer cells. This compound has been shown to inhibit the enzyme phosphatidylinositol 3-kinase (PI3K) in a specific ligand-dependent manner. The precise mechanism of action is not yet understood, but it is thought that 5-bromonicotinoyl chloride may bind to the enzyme and inhibit its activity by hydrogen bonding interactions. This product inhibits PI3K, which is responsible for generating phosphatidylinositol 3,4,5-triphosphate (PIP3). PIP3 activates protein kinase B (AKT), which promotes cell proliferation and inhibits apoptosis. It also inhibits the enzyme phosphodiesterase type 4 (PDE4), which controls intracellular levels of cyclic GMP. PDE4 activity leads to vasodilation and platelet aggregation.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:236.54 g/mol
Formula:C6H3BrClNO2
Purity:Min. 95%
Technical inquiry about: 5-Bromonicotinoyl chloride
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