3-Butylidene phthalide - mixture of cis and trans isomers
CAS:
Ref. 3D-FB19574
1kg
1,544.00€
50g
244.00€
100g
343.00€
250g
662.00€
500g
964.00€
Product Information
Name:3-Butylidene phthalide - mixture of cis and trans isomers
Synonyms:
- 3-Butylidene-1(3H)-isobenzofuranoneButylidenephthalideLigusticum lactone
Brand:Biosynth
Description:Butylidenephthalide is a mixture of the cis and trans isomers. The cis-trans ratio in butylidene phthalide varies with the source material and can range from 0.1 to 1.0. It has been shown that the cis form has a higher level of neurotoxicity than the trans form, which is thought to be due to an increase in the mitochondrial membrane potential. Butylidenephthalide has been shown to cause neuronal death, which may be due to its ability to block calcium ion channels and activate potassium channels, leading to an increase in intracellular sodium levels. Butylidenephthalide also causes balloon injury, as well as cellular physiology changes such as membrane depolarization and increased intracellular sodium concentrations. This chemical can also lead to cancer because it inhibits DNA polymerase activity and signal pathways, causing cell cycle arrest or apoptosis. One study found that butylidenephthalide inhibited angiogenesis by decreasing vascular endothelial
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Chemical properties
Molecular weight:188.22 g/mol
Formula:C12H12O2
Purity:Min. 94.0 Area-%
Color/Form:Yellow Clear Liquid
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