5-(4-Chlorophenyl)-2-furaldehyde
CAS:
Ref. 3D-FC131390
1g
134.00€
2g
200.00€
5g
336.00€
10g
478.00€
500mg
142.00€
Product Information
Name:5-(4-Chlorophenyl)-2-furaldehyde
Synonyms:
- 5-(4-Chlorophenyl)-2-furancarboxaldehyde
Brand:Biosynth
Description:5-(4-Chlorophenyl)-2-furaldehyde (5-CPFA) is an antitubercular drug that inhibits the growth of tuberculosis bacteria by disrupting the synthesis of DNA. It is a functional theory that 5-CPFA inhibits the bacterial enzyme, chalcone hydroxylase, which is involved in the conversion of chalcones to flavones. This inhibition prevents the formation of reactive oxygen species and leads to cell death. The mechanism of action for 5-CPFA has been shown to be due to its ability to form covalent bonds with metal ions such as copper, zinc, and iron. When exposed to ultraviolet radiation, this compound reacts with these metal ions and causes bond cleavage in DNA strands. The resulting damage in DNA strands leads to cell death within hours.
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Chemical properties
Molecular weight:206.62 g/mol
Formula:C11H7ClO2
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C11H7ClO2/c12-9-3-1-8(2-4-9)11-6-5-10(7-13)14-11/h1-7H
InChI key:InChIKey=ROJGJNINTRCMBL-UHFFFAOYSA-N
SMILES:O=Cc1ccc(-c2ccc(Cl)cc2)o1
Technical inquiry about: 5-(4-Chlorophenyl)-2-furaldehyde
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