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2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
CAS:
Ref. 3D-FC138696
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Product Information
Name:2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
Brand:Biosynth
Description:2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one is an industrial chemical that has been used as a potent inhibitor of cyclin dependent kinases. It is one of the first compounds to be identified with this property. 2CPMPY has shown activity against both cyclin D and CDK4, which are essential for mitosis. The compound is synthesized by the intramolecular cyclization of crotonic acid with 2-(chloromethyl)oxirane. This can be done in two ways: by thermal or photochemical means.
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Chemical properties
Molecular weight:263.72 g/mol
Formula:C13H14ClN3O
Purity:Min. 95%
InChI:InChI=1S/C13H14ClN3O/c1-8-6-11(18)17(9-4-2-3-5-9)12-10(8)7-15-13(14)16-12/h6-7,9H,2-5H2,1H3
InChI key:InChIKey=BSKNQSYIDZUXQT-UHFFFAOYSA-N
SMILES:Cc1cc(=O)n(C2CCCC2)c2nc(Cl)ncc12