

c3-Chloro-4-methylpyridine
CAS:
Ref. 3D-FC33804


Product Information
Name:c3-Chloro-4-methylpyridine
Brand:Biosynth
Description:C3-Chloro-4-methylpyridine is an intermediate in the synthesis of tofacitinib, a drug used to treat rheumatoid arthritis. C3-Chloro-4-methylpyridine is prepared by asymmetric hydrogenation of 3,5-dichloro-2,6-dimethylaniline. This process proceeds through an acylation step followed by an asymmetric hydrogenation. The reaction mixture consists of the desired product and a significant amount of 3,5 dichloropyridine. The desired product can be isolated from this mixture using column chromatography or recrystallization.
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Chemical properties
Molecular weight:127.57 g/mol
Formula:C6H6ClN
Purity:Min. 95%