

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methylbromide
CAS:
Ref. 3D-FC43186


Product Information
Name:2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methylbromide
Brand:Biosynth
Description:Pitavastatin calcium is a member of the statin class of lipid-lowering drugs. It is an inhibitor of HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonic acid. Pitavastatin calcium has been shown to inhibit cholesterol synthesis and reduce serum LDL levels in humans. The molecular formula for pitavastatin calcium is C32H40O8Ca, with a molecular weight of 576.13 g/mol and an empirical formula of C32H40O8Ca. This drug has a triclinic crystal structure and crystallizes in the form of needles that are x-ray amorphous. The synthesis involves reacting 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl chloride with calcium hydroxide in dry tetrahydrofuran at 0°C to give the title compound after purification by column chromatography on silica gel
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Chemical properties
Molecular weight:355.03719
Formula:C19H15BrFN
Purity:Min. 95%