2-Chlorobenzyl bromide
CAS:
Ref. 3D-FC46898
Product Information
Name:2-Chlorobenzyl bromide
Brand:Biosynth
Description:2-Chlorobenzyl bromide is a quaternary ammonium salt that is used in the synthesis of acetonitrile and piperidine. 2-Chlorobenzyl bromide has been shown to be an inhibitor of dipeptidyl peptidase IV (DPP-4), which plays a key role in the metabolism of fatty acids. The synthesis of 2-chlorobenzyl bromide can be achieved by reacting acetonitrile with chloroacetone, followed by treatment with potassium hydroxide in methanol. This reaction produces 2-chlorobenzyl chloride, which reacts with sodium methoxide to produce 2-chlorobenzyl bromide and sodium chloride. The preparation of this compound can also be achieved using anion exchange resins. A preparative method for this compound is recrystallization from acetone/hexane mixtures followed by filtration. The centroid of this molecule is
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Chemical properties
Purity:Min. 95%