Dimethyl epipodophyllotoxin
Ref. 3D-FD06000
1g
2,420.00€
Product Information
Name:Dimethyl epipodophyllotoxin
Brand:Biosynth
Description:Dimethyl epipodophyllotoxin is a semisynthetic anticancer agent, which is a derivative of the naturally occurring compound podophyllotoxin, isolated from the rhizomes of Podophyllum species, typically sourced from North American and Himalayan caustic plants. This compound functions primarily as a topoisomerase II inhibitor, disrupting DNA replication and transcription by stabilizing the DNA-enzyme complex and preventing the re-ligation of DNA strands.
The primary application of dimethyl epipodophyllotoxin is in oncology, where it is utilized for its cytotoxic properties. It is most commonly employed as a chemotherapeutic agent in the treatment of various cancers, such as small-cell lung cancer, testicular cancer, lymphomas, and leukemias. Its efficacy is attributed to its ability to induce DNA strand breaks and apoptosis in rapidly dividing tumor cells, thereby arresting their proliferation. Despite its potent antineoplastic effects, the clinical use of dimethyl epipodophyllotoxin necessitates careful management due to potential side effects and the need for precise dosing to minimize toxicity while maximizing therapeutic outcomes.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Purity:Min. 95%
Technical inquiry about: Dimethyl epipodophyllotoxin
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