3,3'-Diindolymethane (synthetic)
CAS:
Ref. 3D-FD14886
1kg
657.00€
2kg
1,067.00€
250g
225.00€
500g
403.00€
Product Information
Name:3,3'-Diindolymethane (synthetic)
Synonyms:
- 3-(1H-Indol-3-ylmethyl)-1H-indole3,3'-Methylenebis-1H-indole
Brand:Biosynth
Description:3,3'-Diindolylmethane, also known as DIM, is natural compound derived from indole. In a recent study, DIM was evaluated as a potential agent for preventing biofilm formation by Streptococcus mutans, which is a major cause of dental caries. The researchers found that DIM significantly inhibited biofilm formation (by 92%) and reduced the production of extracellular polymeric substances (EPS), which are important for biofilm stability particularly under acidic conditions. The study suggests that 3,3'-diindolylmethane has anti-biofilm and anti-virulence properties against S. mutans, and it is a potential candidate for reducing biofilm formation and preventing dental caries.
It has been also reported that 3,3'-diindolymethane can act as a chemopreventive agent. DIM has estrogenic effects without interacting with the binding domain of the estrogen receptors. This study found that DIM could suppress cell growth and disrupt cell cycle progression of young adult mouse colonocytes (YAMCs) in vitro. Moreover, DIM altered gene expression associated with apoptosis and cell proliferation, and it induced transcriptional activity of the estrogen receptor (ER), which was inhibited by an ER antagonist.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:246.31 g/mol
Formula:C17H14N2
Purity:Min. 95%
Color/Form:Powder
Technical inquiry about: 3,3'-Diindolymethane (synthetic)
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.