Di-tert-butyl dicarbonate solution - 2 M in THF
CAS:
Ref. 3D-FD171902
Product Information
Name:Di-tert-butyl dicarbonate solution - 2 M in THF
Brand:Biosynth
Description:Boc-anhydride is widely used for the introduction of the acid-labile Boc-protecting group in organic synthesis. It is extensively used for the protection of amino groups in the synthesis of amino acids, alkaloids, and peptides. Boc-anhydride reacts rapidly and cleanly with the only by-products being carbon dioxide and t-butanol. It is an efficient tert-butoxycarbonylating agent for alcohols and thiols. This group is easily removed by thermolysis or under moderately acidic conditions, such as, treatment with TFA. The Boc protecting group strategy is the preferred method of choice due to its: easy installation, removal, stability towards nucleophiles, and strong basic conditions. In the presence of moisture, it decomposes into tert-butanol and CO2.
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Chemical properties
Molecular weight:218.25 g/mol
Formula:C10H18O5
Purity:Min. 95%
InChI:InChI=1S/C10H18O5/c1-9(2,3)14-7(11)13-8(12)15-10(4,5)6/h1-6H3
InChI key:InChIKey=DYHSDKLCOJIUFX-UHFFFAOYSA-N
SMILES:CC(C)(C)OC(=O)OC(=O)OC(C)(C)C