O-De(3-fluorobenzyl) lapatinib
CAS:
Ref. 3D-FD20805
Product Information
Name:O-De(3-fluorobenzyl) lapatinib
Synonyms:
- 2-Chloro-4-[[6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinyl]amino]phenol
Brand:Biosynth
Description:O-De(3-fluorobenzyl) lapatinib (OFL) is a tyrosine kinase inhibitor that inhibits epidermal growth factor receptor, b-raf, and epidermal growth factor. It also inhibits the serine/threonine protein kinase activity of lapatinib, which is found in the cells of breast cancer. OFL has been shown to inhibit tumor growth in vitro studies. The drug was able to decrease the levels of reactive oxygen species (ROS) in cells by up to 50%. In addition, it may have anti-inflammatory properties due to its ability to inhibit the production of cytokines such as IL-6, TNF-α, and IL-8.
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Chemical properties
Molecular weight:472.95 g/mol
Formula:C22H21ClN4O4S
Purity:Min. 95%