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Desloratadine N-hydroxypiperidine

CAS:

Ref. 3D-FD21215

25mg
314.00€
50mg
354.00€
100mg
749.00€
Desloratadine N-hydroxypiperidine
Biosynth

Product Information

Name:Desloratadine N-hydroxypiperidine
Synonyms:
  • 8-Chloro-6,11-dihydro-11-(1-hydroxy-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Brand:Biosynth
Description:Desloratadine N-hydroxypiperidine is a drug that is used to treat allergic rhinitis and urticaria. It belongs to the class of antihistamines, which block the activity of histamine in the body. Desloratadine N-hydroxypiperidine is a prodrug that has a piperidine moiety attached to its side chain. This prodrug is metabolized into desloratadine, its active form, by esterase enzymes in the liver and blood plasma. The onset of action is rapid after oral administration and the duration of action is 12 hours or more. Desloratadine N-hydroxypiperidine has shown linearity over a wide range of pH values (pH 1 to 10) and ionic strengths (0.1 M to 0.5 M). Optimization was achieved by adjusting elution time, ion-pairing agent, mobile phase composition, organic modifier concentration and column particle
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:326.82 g/mol
Formula:C19H19ClN2O
Purity:Min. 95%
InChI:InChI=1S/C19H19ClN2O/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-21-19(14)18(17)13-7-10-22(23)11-8-13/h1-2,5-6,9,12,23H,3-4,7-8,10-11H2
InChI key:InChIKey=AMIBINHLAUROKH-UHFFFAOYSA-N
SMILES:ON1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1

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