N-Didesmethyl loperamide
CAS:
Ref. 3D-FD21743
Product Information
Name:N-Didesmethyl loperamide
Synonyms:
- 4-(4-Chlorophenyl)-4-hydroxy-a,a-diphenyl-1-piperidinebutanamideR 21345
Brand:Biosynth
Description:N-Didesmethyl loperamide is a synthetic opioid receptor agonist that has been optimized for binding affinity to the μ opioid receptor. The compound has been shown to bind with high affinity and selectivity to the μ opioid receptor, with no efficacy at other opioid receptors. N-Didesmethyl loperamide is an analog of loperamide, which it is more efficient than in binding and activating the μ opioid receptor.
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Chemical properties
Molecular weight:448.98 g/mol
Formula:C27H29ClN2O2
Purity:Min. 95%
InChI:InChI=1S/C27H29ClN2O2/c28-24-13-11-21(12-14-24)26(32)15-18-30(19-16-26)20-17-27(25(29)31,22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14,32H,15-20H2,(H2,29,31)
InChI key:InChIKey=PXJHDOGGBLQFRX-UHFFFAOYSA-N
SMILES:NC(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1