Product Information
Name:6',7'-Dihydroxy bergamottin
Synonyms:
- 4-[[(2E)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one
Brand:Biosynth
Description:Bergamottin is a naturally occurring flavonoid that is found in grapefruit and other citrus fruit. It has been shown to inhibit the activity of the P-glycoprotein (P-gp) transporter in human cells, which may lead to drug interactions. A number of analytical methods have been developed for the determination of bergamottin in biological samples such as humans, rat liver microsomes, and natural compounds. Bergamottin has been shown to be a potent inhibitor of cytochrome P450 enzymes and can inhibit skin cancer development in mice by inhibiting the growth of human keratinocytes (HK-2 cells). Bergamottin also inhibits tumorigenesis in mice by decreasing cell proliferation and inducing apoptosis in hk-2 cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:372.41 g/mol
Formula:C21H24O6
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C21H24O6/c1-13(4-6-18(22)21(2,3)24)8-10-26-20-14-5-7-19(23)27-17(14)12-16-15(20)9-11-25-16/h5,7-9,11-12,18,22,24H,4,6,10H2,1-3H3/b13-8+
InChI key:InChIKey=IXZUPBUEKFXTSD-MDWZMJQESA-N
SMILES:C/C(=C\COc1c2ccoc2cc2oc(=O)ccc12)CCC(O)C(C)(C)O
Technical inquiry about: 6',7'-Dihydroxy bergamottin
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