N,N-Dinitroso-p-phenylenediamine-N,N-diacetic acid
CAS:
Ref. 3D-FD22440
Product Information
Name:N,N-Dinitroso-p-phenylenediamine-N,N-diacetic acid
Synonyms:
- BNN5NaN,N'-1,4-Phenylenebis[N-nitroso]glycinep-Phenylenebis(nitrosoiminoacetic acid)
Brand:Biosynth
Description:N,N-Dinitroso-p-phenylenediamine-N,N-diacetic acid (DNPD) is a water soluble molecule with a pyrimidine nucleus. It has been shown to have anti-inflammatory properties and is used for the treatment of skin conditions such as psoriasis. DNPD also modulates the apoptotic process by inhibiting the proliferation of endothelial cells. DNPD induces apoptosis in human keratinocytes by activating soluble guanylate cyclase, which leads to an increase in intracellular levels of guanosine 3',5'-cyclic monophosphate (cGMP). The activation of cGMP leads to an increase in the production of reactive oxygen species and mitochondrial dysfunction. This ultimately results in cell death.
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Chemical properties
Molecular weight:282.21 g/mol
Formula:C10H10N4O6
Purity:Min. 95%
InChI:InChI=1S/C10H10N4O6/c15-9(16)5-13(11-19)7-1-2-8(4-3-7)14(12-20)6-10(17)18/h1-4H,5-6H2,(H,15,16)(H,17,18)
InChI key:InChIKey=IBQYKJNDVOYCOE-UHFFFAOYSA-N
SMILES:O=NN(CC(=O)O)c1ccc(N(CC(=O)O)N=O)cc1