5,7-Dichloro-8-hydroxyquinoline
CAS:
Ref. 3D-FD34633
1kg
839.00€
2kg
1,355.00€
100g
273.00€
250g
426.00€
500g
569.00€
Product Information
Name:5,7-Dichloro-8-hydroxyquinoline
Brand:Biosynth
Description:5,7-Dichloro-8-hydroxyquinoline (5,7-DC8HQ) is a mitochondrial drug that inhibits mitochondrial functions by binding to the ATP synthase. It has been shown to be effective against bacteria resistant to antimicrobial agents in vivo and also showed genotoxic activity in vitro. 5,7-DC8HQ binds to the magnesium site of the ATP synthase protein and prevents the formation of an intramolecular hydrogen bond, which leads to inhibition of ATP synthesis. This drug has also been shown to cause membrane potential depolarization in mitochondria.
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Chemical properties
Molecular weight:214.05 g/mol
Formula:C9H5Cl2NO
Purity:Min. 95%
Color/Form:White Powder
InChI:InChI=1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI key:InChIKey=WDFKMLRRRCGAKS-UHFFFAOYSA-N
SMILES:Oc1c(Cl)cc(Cl)c2cccnc12
Technical inquiry about: 5,7-Dichloro-8-hydroxyquinoline
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