

2,6-Difluoro-4-hydroxybenzoic acid
CAS:
Ref. 3D-FD75203


Product Information
Name:2,6-Difluoro-4-hydroxybenzoic acid
Brand:Biosynth
Description:2,6-Difluoro-4-hydroxybenzoic acid (DFHB) is a fluorinated derivative of 2,6-difluorobenzoic acid. It has been used as an experimental anticancer agent in cell preparations and in animal models. DFHB has shown to inhibit the production of estrogens by competitively binding to the aromatase enzyme. The mechanistic basis for this inhibition is related to its ability to form a covalent bond with the sulfonyl group of the enzyme. This interaction prevents the binding of substrate and cofactor, leading to decreased synthesis of estrogens.
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Chemical properties
Molecular weight:174.1 g/mol
Formula:C7H4F2O3
Purity:Min. 95%