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3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine

CAS:

Ref. 3D-FD87050

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3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine
Biosynth

Product Information

Name:3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine
Brand:Biosynth
Description:3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine (3DFT) is a nucleoside analogue of thymidine. It has been shown to be an efficient inhibitor of HIV replication in vitro and in vivo. 3DFT is able to inhibit virus production by blocking the viral reverse transcriptase enzyme, which is responsible for copying the viral genomic RNA into DNA. This drug also inhibits the activity of human immunodeficiency virus type 1 integrase, which is an enzyme that catalyses the integration of proviral DNA into host cell chromosomes. 3DFT is a potent inhibitor of HIV infection in vitro and in vivo and has also been shown to inhibit other viruses such as cytomegalovirus, herpes simplex virus types 1 and 2, varicella zoster virus, influenza A virus, coxsackie B4 virus, echovirus 7, and erythrovirus 9.
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Chemical properties

Molecular weight:242.2 g/mol
Formula:C10H11FN2O4
Purity:Min. 95%

Technical inquiry about: 3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine

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