Product Information
Name:Nimesulide-d5
Brand:Biosynth
Description:Nimesulide-d5 is a 5-fluorinated derivative of nimesulide, which is a nonsteroidal anti-inflammatory drug. Nimesulide-d5 has been shown to have an increased terminal half-life in humans and healthy Chinese subjects, as well as reduced glucuronide conjugate formation. This drug also has an enhanced particle size and improved spectral properties for use in chromatographic applications. Nimesulide-d5 is clinically relevant for the treatment of cancer and acetaminophen induced hepatotoxicity. It is metabolized into its active form by cytochrome P450 enzymes, leading to the inhibition of protein synthesis in cancer cells and the prevention of liver toxicity due to acetaminophen overdose.
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Chemical properties
Molecular weight:313.34 g/mol
Formula:C13H7D5N2O5S
Purity:Min. 95%
Technical inquiry about: Nimesulide-d5
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