Ethyl 4-(2-chloroacetylamino)benzoate
CAS:
Ref. 3D-FE54252
Product Information
Name:Ethyl 4-(2-chloroacetylamino)benzoate
Synonyms:
- 4-(2-Chloro-acetylamino)-benzoic acid ethyl ester
Brand:Biosynth
Description:Ethyl 4-(2-chloroacetylamino)benzoate is a reagent that is used to produce aminosulfonyl chlorides. It can be used as an efficient method for the deacylation of thionylated peptides and proteins. The reaction product, which is a sulfonamide, can be hydrolyzed by acid to give the corresponding carboxylic acid. This reagent also has been shown to inhibit the activity of cytosolic phospholipase A2 in human erythrocytes and has been used as a probe for this enzyme in other systems. The inhibition of this enzyme leads to a decrease in arachidonic acid production, which may have therapeutic potential in diseases such as atherosclerosis.
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Chemical properties
Molecular weight:241.67 g/mol
Formula:C11H12ClNO3
Purity:Min. 95%
InChI:InChI=1S/C11H12ClNO3/c1-2-16-11(15)8-3-5-9(6-4-8)13-10(14)7-12/h3-6H,2,7H2,1H3,(H,13,14)
InChI key:InChIKey=ZVRJEYAQESBSSH-UHFFFAOYSA-N
SMILES:CCOC(=O)c1ccc(NC(=O)CCl)cc1