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(E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one
CAS:
Ref. 3D-FF102837
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Product Information
Name:(E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one
Brand:Biosynth
Description:(E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one is a modulator of the secretase enzyme, which belongs to the family of proteases. This drug has been shown to be effective against Alzheimer's disease in animal models. The mechanism of action is not completely known, but it is thought that (E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl imidazol-1-yl)benzylidene]piperidin-2 one inhibits the formation of amyloid beta peptides by inhibiting the production of beta amyloid protein precursor.
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Chemical properties
Molecular weight:419.49 g/mol
Formula:C25H26FN3O2
Purity:Min. 95%
InChI:InChI=1S/C25H26FN3O2/c1-17-15-28(16-27-17)23-11-6-19(14-24(23)31-3)13-21-5-4-12-29(25(21)30)18(2)20-7-9-22(26)10-8-20/h6-11,13-16,18H,4-5,12H2,1-3H3/b21-13+/t18-/m0/s1
InChI key:InChIKey=PUOAETJYKQITMO-LANLRWRYSA-N
SMILES:COc1cc(/C=C2\CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1