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[4-[3-fluoro-5-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]-[5-methylsulfonyl-2-(2,2,2-trifluoro-1-methyl-ethoxy)phenyl]methanone
CAS:
Ref. 3D-FF43104
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Product Information
Name:[4-[3-fluoro-5-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]-[5-methylsulfonyl-2-(2,2,2-trifluoro-1-methyl-ethoxy)phenyl]methanone
Synonyms:
- Bitopertin
Brand:Biosynth
Description:Bitopertin is a drug that inhibits the activity of glycine and glutamate receptors, which are important for neurotransmission. It has been shown to be effective in treating schizophrenia in an intent-to-treat population. Bitopertin is not toxic at doses up to 2000 mg/kg, but has been shown to have interactions with other drugs. This drug binds to the glycine receptor and blocks the glycine binding site, thereby inhibiting postsynaptic actions of glycine. Bitopertin also interacts with the glutamate receptor by binding competitively to the glutamate binding site on the NMDA receptor complex, thereby blocking ion flux through this channel. In addition, bitopertin has inhibitory properties against nicotinic acetylcholine receptors.END>
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Chemical properties
Purity:Min. 95%