

5'-Fluoro-2'-methoxyacetophenone
CAS:
Ref. 3D-FF43401


Product Information
Name:5'-Fluoro-2'-methoxyacetophenone
Brand:Biosynth
Description:5'-Fluoro-2'-methoxyacetophenone is a reactive intermediate that undergoes an electrophilic aromatic substitution with methanol to form the corresponding fluorinated methoxyacetophenone. It can be used to synthesize other fluorinated compounds.
5'-Fluoro-2'-methoxyacetophenone can be activated by reaction with O-chloro-N,O-dimethylhydroxylamine hydrochloride (O-CDMAH) in acetonitrile at room temperature to form the corresponding chloromethylated product. The activated intermediate is then reacted with methanol in methanol/water (1:4) to yield the desired product.
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Chemical properties
Molecular weight:168.16 g/mol
Formula:C9H9FO2
Purity:Min. 95%
InChI:InChI=1S/C9H9FO2/c1-6(11)8-5-7(10)3-4-9(8)12-2/h3-5H,1-2H3
InChI key:InChIKey=CNVGMLMIQIPAFY-UHFFFAOYSA-N
SMILES:COc1ccc(F)cc1C(C)=O