(1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-penten-3-one oxime
CAS:
Ref. 3D-FF95054
Product Information
Name:(1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-penten-3-one oxime
Brand:Biosynth
Description:(1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-penten-3-one oxime is a novel painkiller that has been shown to be effective in acute and chronic models of pain. It acts by inhibiting the voltage gated sodium ion channels (NaV) on nociceptive sensory neurons. This inhibition leads to an attenuation of the response to noxious stimuli. The drug also has a translational effect on humans, which is important for future clinical trials. A double-blind crossover study with coinjection revealed that the drug was safe and well tolerated in healthy human volunteers. This drug could potentially be used for treatment of neuropathic pain, postoperative pain, and cancer pain.
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Chemical properties
Molecular weight:207.24 g/mol
Formula:C12H14FNO
Purity:Min. 95%
InChI:InChI=1S/C12H14FNO/c1-3-12(14-15)9(2)8-10-4-6-11(13)7-5-10/h4-8,15H,3H2,1-2H3/b9-8+,14-12+
InChI key:InChIKey=HKROEBDHHKMNBZ-CHBKHGQFSA-N
SMILES:CCC(=N\O)/C(C)=C/c1ccc(F)cc1