6-Hydroxy bexarotene
CAS:
Ref. 3D-FH23916
2mg
140.00€
5mg
238.00€
10mg
348.00€
25mg
597.00€
50mg
1,973.00€
Product Information
Name:6-Hydroxy bexarotene
Synonyms:
- 4-[1-(5,6,7,8-Tetrahydro-6-hydroxy-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Brand:Biosynth
Description:6-Hydroxy bexarotene is a synthetic retinoid that binds to the retinoic acid receptors in the nucleus and activates gene expression. It is used for the treatment of t-cell lymphoma and cutaneous T-cell lymphoma. 6-Hydroxy bexarotene is metabolized by human liver enzymes, which leads to minimal systemic exposure. The drug has been shown to have transactivating activity in vitro as well as in humans. This activity has been shown to be higher in untreated patients than in those who are on immunosuppressive therapy or other treatments.
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Chemical properties
Molecular weight:364.48 g/mol
Formula:C24H28O3
Purity:Min. 95%
Color/Form:White To Off-White Solid
InChI:InChI=1S/C24H28O3/c1-14-11-20-19(23(3,4)13-21(25)24(20,5)6)12-18(14)15(2)16-7-9-17(10-8-16)22(26)27/h7-12,21,25H,2,13H2,1,3-6H3,(H,26,27)
InChI key:InChIKey=WTWGVKDCAJSUBZ-UHFFFAOYSA-N
SMILES:C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)C(O)CC2(C)C
Technical inquiry about: 6-Hydroxy bexarotene
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