Product Information
Name:2-Hydroxy estrone
Controlled Product
Synonyms:
- 2,3-Dihydroxyestra-1,3,5(10)-trien-17-oneCatecholestrone
Brand:Biosynth
Description:2-Hydroxy estrone is a metabolite of estradiol. It has been shown to be involved in the development of breast cancer and may be a biomarker for the disease. 2-Hydroxy estrone has been found to have genotoxic effects in experimental models and may cause DNA damage. It is also thought to play a role in regulating body weight, reproductive function, mood, and cognition. 2-Hydroxy estrone is an estrogen precursor that binds catechol-o-methyltransferase (COMT) and thereby inhibits COMT activity. This leads to increased levels of dopamine which contributes to breast cancer development. Experimental models have shown that 2-hydroxy estrone can induce tumours in mice by binding to estrogen receptors and stimulating cell division.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:286.37 g/mol
Formula:C18H22O3
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C18H22O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,19-20H,2-7H2,1H3/t11-,12+,14-,18-/m0/s1
InChI key:InChIKey=SWINWPBPEKHUOD-JPVZDGGYSA-N
SMILES:C[C@]12CC[C@@H]3c4cc(O)c(O)cc4CC[C@H]3[C@@H]1CCC2=O
Technical inquiry about: 2-Hydroxy estrone
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