(R)-5-Hydroxymethyl tolterodine
CAS:
Ref. 3D-FH24399
1g
212.00€
2g
339.00€
5g
497.00€
10g
707.00€
25g
1,184.00€
Product Information
Name:(R)-5-Hydroxymethyl tolterodine
Synonyms:
- 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol5-Hydroxymethyl tolterodine
Brand:Biosynth
Description:(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed to
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Chemical properties
Molecular weight:341.49 g/mol
Formula:C22H31NO2
Purity:Min. 98 Area-%
Color/Form:Off-White Powder
InChI:InChI=1S/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11,14,16-17,20,24-25H,12-13,15H2,1-4H3/t20-/m1/s1
InChI key:InChIKey=DUXZAXCGJSBGDW-HXUWFJFHSA-N
SMILES:CC(C)N(CC[C@H](c1ccccc1)c1cc(CO)ccc1O)C(C)C
Technical inquiry about: (R)-5-Hydroxymethyl tolterodine
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