Lapatinib tosylate anhydrous
CAS:
Ref. 3D-FL65053
1g
759.00€
2g
1,259.00€
100mg
265.00€
250mg
447.00€
500mg
621.00€
Product Information
Name:Lapatinib tosylate anhydrous
Synonyms:
- Lapatinib ditosylateGW572016
Brand:Biosynth
Description:Inhibitor of EGFR (ErbB1) and HER2 (ErbB2) receptor tyrosine kinases. Used for sensitization of HER2-overexpressing cancer cells to radiation as well as chemotherapy to tamoxifen- and trastuzumab-resistant cell lines. The compound blocks signalling via Akt and mitogen-activated protein kinase (MAPK) pathways leading to reduced cell survival. In trastuzumab resistant cancer cells, it inhibits HER2 phosphorylation, prevents receptor ubiquitination and causes accumulation of inactive HER2 dimers on the cell surface.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:925.46 g/mol
Formula:C29H26ClFN4O4S•(C7H8O3S)2
Purity:Min. 95%
Color/Form:Off-White Powder
Technical inquiry about: Lapatinib tosylate anhydrous
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