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6-Mercaptopurine hydrate

CAS:

Ref. 3D-FM08197

1kg
1,980.00€
50g
266.00€
100g
397.00€
250g
755.00€
500g
1,186.00€
6-Mercaptopurine hydrate
Biosynth

Product Information

Name:6-Mercaptopurine hydrate
Synonyms:
  • 6-Thiohypoxanthine6-Purinethiol monohydrate
Brand:Biosynth
Description:6-Mercaptopurine is a purine analog that suppresses the production of white blood cells by inhibiting the enzyme thiopurine methyltransferase. It has been used to treat bowel disease and also for long-term suppression of the immune system in patients with autoimmune diseases. 6-Mercaptopurine is metabolized to 6-mercaptopurine, which is then converted to dinucleotide phosphate (dNTP) by group P2 enzymes. This conversion allows 6-mercaptopurine to inhibit dNTP synthesis and cell division. The effects of 6-mercaptopurine are potentiated when given in conjunction with azathioprine, another drug that inhibits purine metabolism. 6-Mercaptopurine is not active against human serum albumin or erythrocytes because it cannot be cleaved into an active form by these proteins. However, it does inhibit enzyme activities such as DNA polymerase, RNA polymerase, and protein
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:152.18 g/mol
Formula:C5H4N4S•H2O
Purity:Min. 97 Area-%
Color/Form:Yellow Powder

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