Product Information
Name:2-Methoxy 17b-estradiol
Controlled Product
Synonyms:
- (17b)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol2-Hydroxyestradiol 2-methyl ether2-Methoxyestra-1,3,5(10)-triene-3,17b-diol
Brand:Biosynth
Description:2-Methoxy 17b-estradiol is a synthetic estrogen that binds to DNA and alters the transcriptional process. It has been shown to induce apoptosis by activating the pro-apoptotic protein Bax and inhibiting the anti-apoptotic protein Bcl-2. This drug inhibits the metabolic response of cancer cells to chemotherapy, leading to a decrease in tumor size, and can be used as an implantable device for treating cancer. 2-Methoxy 17b-estradiol also has minimal toxicity in comparison to other estrogens, with no significant cytotoxicity observed in cells of reproductive tissues or endocrine organs, nor any significant toxic effects on liver function tests or serum lipids.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:302.41 g/mol
Formula:C19H26O3
Purity:Min. 95%
Color/Form:White/Off-White Solid
InChI:InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1
InChI key:InChIKey=CQOQDQWUFQDJMK-SSTWWWIQSA-N
SMILES:COc1cc2c(cc1O)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12
Technical inquiry about: 2-Methoxy 17b-estradiol
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