Mevastatin hydroxy acid sodium salt
CAS:
Ref. 3D-FM25992
Product Information
Name:Mevastatin hydroxy acid sodium salt
Synonyms:
- (b-R,?R,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-b,?-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid sodium salt[1S-[1a(b-S*,?S*),2a,8b(R*),8a-a]]-1,2,6,7,8,8a-Hexahydro-b,?-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naph
Brand:Biosynth
Description:Mevastatin is a cholesterol-lowering drug that belongs to the class of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. It is used in the treatment of hypercholesterolemia, which is an excess of cholesterol in the blood. Mevastatin inhibits the biosynthesis of cholesterol by competitively inhibiting HMG-CoA reductase, which is an enzyme involved in the production of mevalonic acid from acetyl-CoA and acetoacetyl-CoA. This drug also inhibits the synthesis of pravastatin through a cytochrome P450 enzyme system. Mevastatin has been shown to inhibit transcriptional regulation in human skin fibroblasts and to downregulate mRNA levels for gene products involved in cellular proliferation.
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Chemical properties
Molecular weight:430.51 g/mol
Formula:C23H35NaO6
Purity:Min. 95%