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Methyl 4-bromomethylbenzoate

CAS:

Ref. 3D-FM38827

100g
140.00€
250g
188.00€
500g
261.00€
Methyl 4-bromomethylbenzoate
Biosynth

Product Information

Name:Methyl 4-bromomethylbenzoate
Synonyms:
  • 4-(Bromomethyl)benzoic acid methyl ester
Brand:Biosynth
Description:Methyl 4-bromomethylbenzoate is an aryl halide with the chemical formula CHBr. It is an orally effective and selective apoptosis pathway inhibitor that blocks the release of tumor necrosis factor-α (TNF-α) induced by lipopolysaccharides in monocytes. Methyl 4-bromomethylbenzoate has also been shown to inhibit matrix metalloproteinase activity in vitro, which may be due to its ability to block the cleavage of proteoglycan precursors. The molecular modeling studies have revealed that this agent binds to DNA through a hydrophobic pocket, which inhibits transcription and replication. Methyl 4-bromomethylbenzoate has also been shown to be active against cancer cells and induce apoptosis through caspase activation and mitochondrial dysfunction.
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Chemical properties

Molecular weight:229.07 g/mol
Formula:C9H9BrO2
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C9H9BrO2/c1-12-9(11)8-4-2-7(6-10)3-5-8/h2-5H,6H2,1H3
InChI key:InChIKey=NLWBJPPMPLPZIE-UHFFFAOYSA-N
SMILES:COC(=O)c1ccc(CBr)cc1

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