Product Information
Name:Navitoclax
Synonyms:
- 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)me
Brand:Biosynth
Description:A Bad-like BH3 mimetic with strong affinity for Bcl-xl, Bcl-2 and Bcl-w that promotes BIM-mediated apoptosis. Enhanced efficacy when combined with other chemotherapies in xenograft models of B-cell malignancies and SCLC. Has senolytic effects on senescent cells, demonstrating revival of aged HSCs in vivo.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:974.62 g/mol
Formula:C47H55ClF3N5O6S3
Purity:Min. 98 Area-%
Color/Form:Powder
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