Pramlintide
CAS:
Ref. 3D-FP156979
Product Information
Name:Pramlintide
Brand:Biosynth
Description:Pramlintide is a synthetic, short-acting insulinotropic peptide that has been shown to reduce postprandial glucagon secretion and delay gastric emptying. It also has a number of physiological effects, including the activation of ATP-sensitive potassium channels, inhibition of oxidative phosphorylation, and induction of mitochondrial membrane potential. Pramlintide is approved for use in the treatment of type 1 and type 2 diabetes mellitus. The drug binds to the glucagon receptor on pancreatic alpha cells and stimulates insulin release from beta cells in a glucose-dependent manner. Pramlintide has been shown to have no significant effect on glycemic control when used as an adjunct to insulin therapy in patients with type 2 diabetes mellitus. This drug may also cause hypoglycemia when used alone or with other antihyperglycemic agents such as sulfonylureas or meglitinides.
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Chemical properties
Molecular weight:3,949.39 g/mol
Formula:C171H267N51O53S2
Purity:Min. 95%
Color/Form:White To Off-White Solid