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Purmorphamine

CAS:

Ref. 3D-FP27264

2mg
155.00€
5mg
241.00€
Purmorphamine
Biosynth

Product Information

Name:Purmorphamine
Synonyms:
  • 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
Brand:Biosynth
Description:Purmorphamine is a cell factor that belongs to the group of morphogens. It is structurally related to dopamine and has been shown to be effective in the treatment of Parkinson's disease. Purmorphamine is involved in the regulation of neuronal survival, differentiation, proliferation, and axon guidance. Purmorphamine binds to a receptor on neurons called the cholinergic receptor, which stimulates a G-protein linked signal transduction pathway. This leads to an increase in intracellular calcium levels and activation of protein kinase C. Purmorphamine also has anti-inflammatory effects and can inhibit leukemia inhibitory factor (LIF). It has been shown to be effective against LPS-induced inflammatory responses by inhibiting protein synthesis. Purmorphamine also inhibits cancer cells through its ability to stimulate growth factor-β1 (GF-β1) gene expression.
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Chemical properties

Molecular weight:520.63 g/mol
Formula:C31H32N6O2
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)
InChI key:InChIKey=FYBHCRQFSFYWPY-UHFFFAOYSA-N
SMILES:c1ccc2c(Oc3nc(Nc4ccc(N5CCOCC5)cc4)c4ncn(C5CCCCC5)c4n3)cccc2c1

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