5-Pyridin-4-yl-2H-pyrazol-3-ylamine
CAS:
Ref. 3D-FP51268
1g
336.00€
100mg
140.00€
250mg
167.00€
500mg
236.00€
Product Information
Name:5-Pyridin-4-yl-2H-pyrazol-3-ylamine
Brand:Biosynth
Description:5-Pyridin-4-yl-2H-pyrazol-3-ylamine is a potent inhibitor of b-raf, a protein kinase that is involved in the regulation of cell proliferation and differentiation. It is used as a research tool for studying the role of b-raf in cancer. 5-Pyridin-4-yl-2H-pyrazol-3-ylamine has been shown to have similar activity to other inhibitors of bRaf. It binds to the ATP binding site on bRaf and prevents phosphorylation of serine residues in the activation loop by ATP. This inhibition prevents activation of the kinase and reduces tumor growth in cancer models.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:160.18 g/mol
Formula:C8H8N4
Purity:Min. 95%
Color/Form:White/Off-White Solid
InChI:InChI=1S/C8H8N4/c9-8-5-7(11-12-8)6-1-3-10-4-2-6/h1-5H,(H3,9,11,12)
InChI key:InChIKey=MDRGSALNBWSYJX-UHFFFAOYSA-N
SMILES:Nc1cc(-c2ccncc2)[nH]n1
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