Product Information
Name:AZD-7648
Brand:Biosynth
Description:AZD-7648 is a selective inhibitor of DNA-dependent protein kinase (DNA-PK), which is a pivotal enzyme involved in the non-homologous end joining (NHEJ) pathway of DNA repair. This product is derived from extensive chemical synthesis and optimization, designed for its specificity and efficacy in inhibiting DNA-PK activity. The mode of action involves binding to the ATP-binding site of DNA-PK, thereby obstructing its ability to facilitate the repair of double-strand DNA breaks.
The primary application of AZD-7648 is in cancer research, particularly in studying cancers that rely heavily on NHEJ for DNA repair. By inhibiting DNA-PK, AZD-7648 has the potential to sensitize tumor cells to radiation and certain chemotherapy agents that induce DNA damage. Researchers utilize this compound to explore the mechanics of DNA repair and to develop potential therapeutic strategies for tumors deficient in alternative repair pathways. The specificity of AZD-7648 allows for a focused examination of DNA-PK’s role in cell survival and its potential as a therapeutic target in oncology.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:380.4 g/mol
Formula:C18H20N8O2
Purity:Min. 98 Area-%
Color/Form:Powder
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