Senecionine N-oxide
CAS:
Ref. 3D-FS161594
1mg
303.00€
2mg
455.00€
5mg
730.00€
10mg
1,044.00€
25mg
1,966.00€
Product Information
Name:Senecionine N-oxide
Brand:Biosynth
Description:Senecionine N-oxide is a pyrrolizidine alkaloid N-oxide, which is a naturally occurring chemical compound known for its toxicological properties. It is primarily sourced from plants belonging to the Senecio genus, which are widely distributed across various geographical regions. The mode of action of Senecionine N-oxide involves its bioactivation in the liver, where it is converted to reactive pyrrolic metabolites. These metabolites can form adducts with cellular macromolecules such as DNA and proteins, leading to hepatic necrosis and potentially mutagenic effects.
Senecionine N-oxide is primarily studied in the field of toxicology to understand its impact on human health and livestock. It serves as a model compound for investigating the metabolic pathways and toxicological mechanisms of pyrrolizidine alkaloids. Additionally, it is used as a reference compound in analytical studies aiming to identify and quantify pyrrolizidine alkaloid contamination in food and herbal products. Understanding its mode of action and effects is crucial for developing risk assessment strategies and mitigation measures for exposure to pyrrolizidine alkaloid-containing plants.
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Chemical properties
Molecular weight:351.39 g/mol
Formula:C18H25NO6
Purity:Min. 95%
Technical inquiry about: Senecionine N-oxide
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