2-(Trifluoromethyl)benzimidazole
CAS:
Ref. 3D-FT37003
10g
228.00€
25g
343.00€
50g
534.00€
100g
722.00€
Product Information
Name:2-(Trifluoromethyl)benzimidazole
Brand:Biosynth
Description:2-(Trifluoromethyl)benzimidazole (TFB) is a synthetic trifluoromethyl-substituted benzimidazole. It has been shown to have potent tuberculostatic activity and is effective against a wide range of protozoan parasites, including Leishmania, Trichomonas vaginalis, and Giardia lamblia. TFB binds to the target molecule by forming hydrogen bonds with the amino acid side chains on the enzyme's surface. TFB inhibits energy metabolism in cancer cells and causes them to undergo apoptosis through activation of caspase-3. The diploid rat liver cell line HepG2 was used for in vivo studies that showed that TFB inhibits ethylene diamine deaminase activity, which is required for the synthesis of purines and pyrimidines from ethylene diamine.
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Chemical properties
Molecular weight:186.13 g/mol
Formula:C8H5F3N2
Purity:Min. 95%
Color/Form:Powder
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