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Tryptanthrin

CAS:

Ref. 3D-FT66458

25mg
227.00€
50mg
473.00€
100mg
589.00€
250mg
1,126.00€
500mg
1,878.00€
Tryptanthrin
Biosynth

    Product Information

    Name:Tryptanthrin
    Synonyms:
    • Indolo[2,1-b]quinazoline-6,12-dione
    Brand:Biosynth
    Description:Tryptanthrin is a natural compound that has been shown to inhibit the activity of P-glycoprotein (P-gp) by binding to its basic protein. Tryptanthrin has also been shown to be cytotoxic in bowel disease. Tryptanthrin has a significant cytotoxicity against HL60 cells, which is due to its ability to inhibit the activity of cyclin D2. This agent also inhibits the proliferation of HL60 cells induced by oxidative injury, and can be used as an anti-cancer therapeutic. Molecular docking analysis suggests that tryptanthrin binds with high affinity to the ATPase region of P-gp.
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:248.24 g/mol
    Formula:C15H8N2O2
    Purity:Min. 95%
    Color/Form:White Powder
    InChI:InChI=1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H
    InChI key:InChIKey=VQQVWGVXDIPORV-UHFFFAOYSA-N
    SMILES:O=C1c2ccccc2-n2c1nc1ccccc1c2=O

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