Product Information
Name:Dehydro simvastatin
Synonyms:
- Simvastatin Impurity C
Brand:Biosynth
Description:Dehydro simvastatin is a high-yielding, efficient, and selective synthesis of simvastatin. It is prepared from the commercially available (2S)-2-[(1E,3R)-3-hydroxybut-1-enyl]oxirane using a three-component reaction with chlorotrimethylsilane and sodium chloride to yield the desired product in good yields. The reaction can be performed in a variety of solvents including dichloromethane, chloroform, tetrahydrofuran, or methanol. Dehydro simvastatin has been used for pharmaceutical formulations as an active ingredient of HMG CoA reductase inhibitors. It also has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.
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Chemical properties
Molecular weight:400.55 g/mol
Formula:C25H36O4
Purity:Min. 95%
Color/Form:Colorless Powder
Technical inquiry about: Dehydro simvastatin
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